In the atezolizumab trials [20,23,24,25,29], levels were considered high (TC3 or IC3) when PD-L1 expression was recorded on at least 50% of tumor cells or at least 10% of tumor-infiltrating immune cells (TIICs) by immunohistochemistry; levels were considered low–intermediate, or TC1/2 or IC1/2, when expression was reported on at least 1% of tumor cells or TIICs and less than 50% of tumor cells or less than 10% of TIICs by immunohistochemistry; and PD-L1-negative status, or TC0 and IC0, was determined when expression was reported on less than 1% of tumor cells and TIICs. Here, CD274 is linked to neoplasm.