SOD1 and Hepatic fibrosis: An in vivo study demonstrated that, selenium-GSH-enriched probiotics could effectively increase the hepatic GSH level and the activities of GSH-Px and SOD, as well as attenuate carbon tetrachloride-induced hepatic oxidative stress and liver fibrosis in rats; this study also demonstrated that this combination probiotics had better protective effects on liver fibrosis than selenium or GSH alone [44].