It is worth noting that one epitope (786QILPDPLKPTKRSFIEDLLFNKVTLA811) located in the S2 subunit of the SARS-CoV S protein is an important linear B-cell epitope capable of eliciting the production of a neutralizing antibody (NAb) identified in patients who recovered from SARS-CoV infection (Table S2) [13]. Here, PROS1 is linked to severe acute respiratory syndrome.