A retrospective, single-center study of 99 cases of COVID-19 in Wuhan Jinyintan Hospital revealed that severe patients had high levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST), myocardial zymogram, blood urea nitrogen and serum creatinine, all of which were implicated with multiple organ damage. The gene discussed is GPT; the disease is COVID-19.