In addition, STAT5a-regulated NOX5-L expression increased the invasion and migration of human SK-BR-3 breast adenocarcinoma cells [23] and the inhibition of STAT5a by N-α-acetyltransferase protein (Naa10p) led to the suppression of cell motility and invasion in human MCF-7 and MDA-MB-231 BCa cells [24]. This evidence concerns the gene STAT5A and breast adenocarcinoma.