Our results revealed that KRT80, AJUBA, S100A11, TMEM9, SLC39A10, FOXQ1, and CLDN1 were upregulated whereas the expressions of SPIB, KRT24, PHLPP2, PLP1, BEST4, ZZEF1, CCDC68, CA7, and C11orf86 were downregulated in colon cancer. This evidence concerns the gene SLC39A10 and colonic neoplasm.