To this aim, we determined the gene expression profile of GIST‐T1 cells in function of LIX1 expression (GIST‐T1‐ShLIX1#1, GIST‐T1‐ShLIX1#2 and vs GIST‐T1‐Scrambled cells) using a high‐throughput RNA‐sequencing approach. The gene discussed is LIX1; the disease is gastrointestinal stromal tumor.