The results elucidated that has_circ_CCNB1 was positively correlated whereas has_circ_0009024 was negatively correlated with IL‐6 and TNF‐α, which contribute to confirming the accuracy of has_circ_CCNB1 and has_circ_0009024 in the diagnosis of T2DM. This evidence concerns the gene IL6 and type 2 diabetes mellitus.