Consistent with our previous report, RKIP is significantly downregulated in NPC, particularly in radioresistant NPC (Fig. 6a, Table 1), whereas, the level of NRF2 and NQO1 is remarkably upregulated in NPC specimens (Fig. 6a, Table 1), especially in radioresistant ones (Fig. 6a, Table 1). This evidence concerns the gene NFE2L2 and nasopharyngeal carcinoma.