Indeed, the qPCR results indicated that the expression of miR-450b-5p was decreased by RKIP depletion in CNE2 cells (Fig. 4b, left arm), whereas, increased by RKIP overexpression in NPC cells (Fig. 4b, right arm), suggesting that RKIP could positively regulate miR-450b-5p in NPC. This evidence concerns the gene PEBP1 and nasopharyngeal carcinoma.