The present study reveals that in NPC cells, Gal-9 significantly up-regulates the genes encoding cytokines and chemokines related to myeloid cell differentiation and expansion, including IL-1β, IL-1α, IL-6, CXCL8, CX3CL1, CCL22, and CCL-5. This evidence concerns the gene CX3CL1 and nasopharyngeal carcinoma.