ITGB5 and migraine disorder: Cross-trait meta-analysis between migraine subtypes (MA and MO) and BP showed that previous reported migraine loci, including PHACTR1, LRP1, and FHL5, were shared between both migraine subtypes and BP while locus rs4141663 implicating ITGB5 was genome-wide significant in cross-trait meta-analysis between MO and BP measurements, but not MA (Supplementary Tables 9–14).