ADSL and Alzheimer disease: In Alzheimer’s disease (AD) brains, AMPs are highly expressed in glial cells, and a key protein in AD pathology, amyloid-β peptide, has antimicrobial activity (Soscia et al. 2010; Kagan et al. 2012; Kumar et al. 2016; Spitzer et al. 2016; Tsuda and Lim 2018).