To illustrate that even well-known chimeric oncogenic transcripts can be produced by gene-intergenic fusions, we show four such instances in Fig. 2: TMPRSS2-ETV4UIB (3 cases in PRAD), TMPRSS2-ERGUIB (1 case in PRAD), TBL1XR1-PIK3CAUIB (1 case in PRAD), and PTPRK-RSPO3UIB (2 cases in COAD/READ). The gene discussed is TMPRSS2; the disease is prostate adenocarcinoma.