Indeed, it has been shown that CCT6A promote the survival and metastasis of NSCLC cells in a TGF-β signaling-dependent manner; thus, CCT6A may display a close correlation with metastasis in patients with high TGF-β level, while more explorations are needed to validate this issue [16]. The gene discussed is TGFB1; the disease is non-small cell lung carcinoma.