Moreover, IHC score was used to semi-quantitatively determine the CCT6A expression, which showed that CCT6A IHC score was increased in tumor tissue than adjacent tissue (Supplementary Figure 2A), and ROC curves displayed that CCT6A could discriminate NSCLC tissue from adjacent tissue (area under the curve (AUC) 0.708, 95%CI 0.671–0.744) (Supplementary Figure 2B). The gene discussed is CCT6A; the disease is neoplasm.