Moreover, multivariate Cox’s regression showed that tumor CCT6A high expression (P < 0.001, HR 1.659 (95%CI 1.318–2.089)) independently predicted poor DFS, meanwhile, poor differentiation (P = 0.006, HR 1.281 (95%CI 1.073–1.530)), LYN metastasis (P < 0.001, HR 2.227 (95%CI 1.757–2.824)) as well as abnormal CEA (>5.0 ng/mL) (P = 0.004, HR 1.405 (95%CI 1.114–1.772)) were independent predictive factors for worse DFS. This evidence concerns the gene CEACAM5 and neoplasm.