Among the texture features, correlation and sum entropy were significantly higher in IDH-mutant tumours than in the IDH-wildtype (p < 0.0001), while sum square, sum average, sum variance, entropy and difference variance features were significantly lower (p ≤ 0.0001) in IDH-mutant gliomas compared to IDH wildtype gliomas. Here, IDH2 is linked to central nervous system cancer.