Lastly, gene ontology (GO) analyses, which were performed to understand the biological functions of 145 biomarkers of our final paclitaxel response predictor, showed that COL1A1, RPH3AL, and THSD4 were the most significantly associated with breast neoplasm function (false discovery rate (FDR) P < 0.001). The gene discussed is RPH3AL; the disease is breast neoplasm.