Results for food intake were similar to those of the control diet phase, but significant interaction emerged since it was increased in 3xTg-AD/GFAP-sgp130Fc (~17.8% vs GFAP-sgp130Fc) but not in 3xTg-AD (vs WT) females (p = 0.049 R2 = 0.50). Here, GFAP is linked to Alzheimer disease.