3.3. SIRT1, and Ku70-Deacetylations, are Increased in Human IPF- and in BLM-Lung Myofibroblasts. Concomitantly, BLM-Treated Chimeric Mice, with Specific SIRT1-Deficiency, in Mesenchymal Cells, Increase Acetylated-Ku70, Decrease FLIP and Show Less Fibrosis. The gene discussed is SIRT1; the disease is fibrosis.