BRCA1 and triple-negative breast carcinoma: To further validate our previous findings, we selected three different human triple negative breast cancer (TNBC) cell lines, representative of different BRCA and HRR status (Figure 3A,E,I and Table S1)—Hs578T and MDA-MB-468 as BRCAwt and HCC1937 as BRCA1 mutant.