PIN1 and cancer: Presently, several Pin1 inhibitors have been developed, such as miR-200b, miR-200c, and miR296-5p, the small molecules all-trans retinoic acid (ATRA) and KPT-6566, and the natural compound Juglone, which all showed anti-cancer activity in different types of cancer [125,126,127,128,129,130].