Of note, a combination of different approaches has been applied to study the platelet N-glycosylation status in PMM2-congenital disorder of glycosylation (PMM2-CDG) patients, including immunoblotting, lectin-based enrichment of glycosylated proteins and expression of different membrane platelet N-glycoproteins by flow cytometry, as well as by platelet N-glycoproteome analysis with 2D-DIGE. Here, PMM2 is linked to congenital disorder of glycosylation.