As it would exceed the scope of this broad review to describe the specific transgenic Pkd1 and Pkd2 murine models, here again we refer our reader to the recently published chapter describing those models in detail, as well as the divers techniques used to assess the PKD phenotype in those animals, in the book Polycystic Kidney Disease edited by Jinghua Hu and Yong Yu [181]. This evidence concerns the gene PKD1 and polycystic kidney disease.