In female participants, in the univariate analysis, age (p = 0.0188), presence of LC (p = 0.0003), serum albumin level (p = 0.0010), AC (p = 0.0491), TSF (p = 0.0263), and CC (p < 0.0001) were observed to be significant factors associated with the presence of frailty (Table 5). This evidence concerns the gene ALB and laryngotracheoesophageal cleft.