The median values of pretreatment ATX levels in patients with post-SVR HCC were 1.56 mg/L in male patients and 2.37 mg/L in female patients, and these values were close to the cutoff values for predicting liver cirrhosis from reagent’s attached document (male, 1.69 mg/L; female, 2.12 mg/L). Here, ENPP2 is linked to hepatocellular carcinoma.