In EC, paired analysis showed significantly upregulated Ki67 and CDKN1A, markers of metabolic reprogramming ODC1 and SLC2A1, mediators of angiogenesis HIF1A and VEGFA, mediators of inflammation and immunity NOS2, CCL2, PTGS2, IL10 and its receptor IL10Ra and downregulated mesenchymal marker ACTA2 in tumor as compared to non-cancerous tumor-adjacent tissue. This evidence concerns the gene PTGS2 and neoplasm.