The expression of ACTA2, HIF1A, and VEGFA was independently associated with TJP1 in non-cancerous tissue, explaining 90% in its variability, and BCL2, HIF1A, CDKN1A, and PTGS2 were independently associated with TJP1 in gastric tumors, explaining 98% in gene variability. This evidence concerns the gene PTGS2 and gastric neoplasm.