In addition to differences regarding non-transformed tissue, gastric tumors had higher than esophageal ones expression of BCLxL, CDKN1A, VEGFA, ACTA2, CLDN2, TJP1, and IL7Ra. Of note, markedly higher IL-7 protein upregulation in GC than EC has previously been reported [17]. The gene discussed is CLDN2; the disease is gastric neoplasm.