Olasehinde et al. reported that four South African macroalgae such as Gracilaria gracilis, Ulva lactuca, Ecklonia maxima, and Gelidium pristoides exhibited anti-cholinesterase, anti-BACE1, and Aβ aggregation inhibitory activities, indicating that these types of seaweed could be potential sources of anti-AD agents [35]. Here, BCHE is linked to Alzheimer disease.