APOA1 and metabolic syndrome: Several observations seem to reduce the importance of HDL in cardio-protection [80]: MCE to whole plasma better correlates with APOB and non-HDL-C concentrations than with HDL-C or APOA1; the magnitude of MCE to whole plasma of MetS patients is greater than that to normolipidemic patients; weight loss among MetS patients reduces the magnitude of MCE to their plasma to that of normolipidemic patients.