In addition, it is possible that ROS/RNS cause lateralization of Cxs so that Cxs may be found in an aberrant location, i.e., increasing the expression of hemichannels while reducing gap junction Cxs—as it occurs in cardiac muscle Cx43 of Duchenne muscular dystrophy mice [77]. The gene discussed is GJA1; the disease is Duchenne muscular dystrophy.