ELP2 and cancer: Of them, mutations in NSUN2 have also been linked to the Dubowitz syndrome [156], the Noonan-like syndrome [157], and to different cancer types [158], while ELP2 is one subunit of the Elongator complex that is involved in U34 modifications of a subset of tRNAs and in which misfunction due to mutated components has also been linked to familial dysautonomia, amyotrophic lateral sclerosis, asthma, and cancer [152].