However, compared with mouse models of renal ischemia–reperfusion injury, sNGAL increased modestly in cisplatin-induced AKI and was only, on average, 2.65-fold higher 24 h after 20 mg/kg cisplatin administration, while NGAL levels could increase up to 300-fold in blood after 24 h reperfusion in the ischemia–reperfusion injury model [22]. Here, LCN2 is linked to acute kidney injury.