After depletion of ribosomal RNA, followed by fragmentation with divalent cation buffers in elevated temperature, we prepared six sequencing libraries for two groups, each group containing three libraries (Group 1: sham- SH1, SH2, and SH3, and group 2: stroke- ST2, ST3, and ST4), using Illumina’s TruSeq-stranded-total-RNA-sample preparation protocol. Here, MMP11 is linked to Stroke.