In contrast to oncogenic lncRNAs that upregulate MMPs to enhance invasion, lncRNA FOXF1 adjacent non-coding developmental regulatory RNA (FENDRR) upregulates tissue inhibitors of MMP-2 (TIMP2) by sponging mir-176 to suppress NSCLC migration, invasion, and metastasis [102]. Here, MMP2 is linked to non-small cell lung carcinoma.