TLR4 and rheumatoid arthritis: Similar analysis for MG and its animal models based on Table 1 yields TLR3-TLR7 and TLR4-TLR7 synergisms, while RA (and its animal models) yields synergisms between TLR2-TLR4, TLR4-TLR7 and TLR2-NOD2 (Table 2).