The estimated coefficient of GAL for TARGET was β=0.258 with the marginal hazard ratio of 1.29 (95% CI: 1.10–1.52) and the p-value of 0.0016, while the estimated parameter for GSE19710 was β=0.650 with the hazard ratio of 1.91 (95% CI: 1.18–3.10) and p value of 0.008 (Supplementary Table S4), indicating that GAL was an independent predictor of overall survival (OS) for HR-NB patients in addition to MYCN amplification and age. This evidence concerns the gene GAL and neuroblastoma.