CXCR4 and acute myeloid leukemia: Flow cytometry results showed that LY2510924 partially reduced binding of the anti-CXCR4 antibody 12G5 to surface CXCR4 in a concentration-dependent fashion in FLT3-ITD-AML MV4–11 and completely in MOLM-14 cells (Figure 1E,F).