About ddPCR, two other groups already proposed it as a good technique for IDH2 mutations detection: In 2018, Petrova et al. used this method for screening 90 AML patients: IDH1/IDH2 mutations were detected in 22 cases (24%), with only one case carrying both IDH1 and IDH2 mutations [8]. The gene discussed is IDH1; the disease is acute myeloid leukemia.