NAGA and neoplasm: Previously, a double-blind clinical trial evaluated the effects of AC in combination with chemotherapy and showed that the mean 6-month survival rate was not significantly different between the AC and placebo groups due to the short treatment of only 30 days.[15] In this case, the result of the nagalase test and the follow-up MRI examination at the fifth month of adjuvant therapy plus AC revealed that administration of 10 g of AC for longer periods (over 3 to 5 months) was more beneficial for the patient in terms of tumor regression and clinical outcomes.