Sanoja-Flores et al (2018) reported that CTPC were detected in PB in 100% of MM and in 59% of MGUS patients.[19] Earlier studies showed that detection of CTPC in PB in MGUS is about 19% to 37% and 50% to 75% in MM[41,42] indicating the modern improvement in NGF sensitivity. Here, NGF is linked to Miyoshi myopathy.