Compared with LV-Sox2ot- or LV-Egr1-treated AAA mice, these two mice further injected with extra LV-miR-145 individually both displayed reduced levels of COX-2, NO, IL-1β, IL-6, TNF-α, and MDA, yet increased levels of SOD (p < 0.05) (Figure 7F, 7G), suggesting that the stimulating effects of lncRNA Sox2ot and Egr1 on inflammation and oxidative stress in AAA mice could be counteracted by overexpression of miR-145. This evidence concerns the gene SOD1 and triple-A syndrome.