EGR1 and triple-A syndrome: Compared with AAA mice injected with LV-Sox2ot and LV-Egr1, AAA mice injected with LV-Sox2ot + LV-miR-145 and LV-Egr1 + LV-miR-145 showed elevated SMC and decreased macrophages (p < 0.05) (Figure 7D, 7E).