The findings of ELISA proved that compared with the normal mice, AAA mice injected with LV-miR-NC and LV-NC-inhibitor showed increased levels of cyclooxygenase 2 (COX-2), NO, interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, MDA, cleaved caspase-3, NADPH oxidase 4 (NOX4), inducible nitric oxide synthase (iNOS), and p47phox, however, decreased levels of SOD, collagen I, and collagen III were observed, respectively, indicating that levels of inflammation and oxidative stress in AAA mice were higher than those in normal mice. This evidence concerns the gene CASP3 and triple-A syndrome.