PTGS2 and triple-A syndrome: Moreover, ELISA results exhibited that compared with the AAA mice injected with LV-NC, AAA mice overexpressing lncRNA Sox2ot or Egr1 showed increased levels of COX-2, NO, IL-1β, IL-6, TNF-α, and MDA, however, decreased the levels of SOD, which indicated that upregulation of lncRNA Sox2ot and Egr1 stimulated the strength of inflammation and oxidative stress in AAA mice.