Compared with AAA mice injected with LV-miR-NC, AAA mice injected with LV-miR-145 showed reduced levels of COX-2, NO, IL-1β, IL-6, TNF-α, MDA, cleaved caspase-3, NOX4, iNOS, and p47phox, whereas increased levels of SOD, collagen I, and collagen III were observed. The gene discussed is NOS2; the disease is triple-A syndrome.