Moreover, ELISA results exhibited that compared with the AAA mice injected with LV-NC, AAA mice overexpressing lncRNA Sox2ot or Egr1 showed increased levels of COX-2, NO, IL-1β, IL-6, TNF-α, and MDA, however, decreased the levels of SOD, which indicated that upregulation of lncRNA Sox2ot and Egr1 stimulated the strength of inflammation and oxidative stress in AAA mice. The gene discussed is SOD1; the disease is triple-A syndrome.