CD4 and hepatocellular carcinoma: In the ICGC cohort, significantly higher proportions of resting CD4 memory T cells were found in HCC patients with higher C2 expression, while significantly higher proportions of macrophage M0 cells, activated CD4 memory T cells, and Treg cells were found at HCC patients with lower C2 expression (all p < 0.05, Figure 4(c)).