The statins above mentioned were able to decrease the cell proliferation and tumor growth in several cellular models, such as lung cancer (A549, NCI-H292), colorectal cancer (HCT-116, HCT-116 p53), and AGS human gastric carcinoma cells, and in a xenograft female BALB/c nude mouse model of A549 lung cancer (Lin et al., 2008). This evidence concerns the gene TP53 and neoplasm.