Wei et al. (2016a) tested the molecules in C57BL/6, BALB/c, NOD/SCID mice, and Apc(Min/+) colorectal cancer (CRC) mouse models obtaining inhibition of metastasis, angiogenesis, and cancer stemness; furthermore, such compounds boosted the effect of oxaliplatin in the aforementioned CRC mouse models. Here, APC is linked to colorectal carcinoma.