Although in immune competent mice ΔRPS13 does not recrudesce with ATc treatment initially, beyond 3 days after infection, we found that when ATc was added after treatment of the immune compromised mice with JAG21 dosed intraperitoneally for 14 days, the dormant ΔRPS13 parasite could still recrudesce after JAG21 treatment was discontinued and tetracycline added (Figure 6C and Supplemental Figure 2). Here, ATM is linked to infection.