PNN and colorectal carcinoma: Consistent with our prediction, we found that the expression of hsa-miR-6833-3p (Spearman's correlation, r = −0.4546, P < 0.05), hsa-let-7i-3p (Spearman's correlation, r = −0.4631, P < 0.05) and hsa-miR-1301-3p (Spearman's correlation, r = −0.4208, P < 0.05) showed negative correlation with levels of circ-PNN in CRC (Figures 7B–D).