NPPB and hydrops fetalis: Therefore, decreased levels of NT − proBNP < 1000 pg/ml as a result of HF therapy was associated with lower 180-day mortality and readmission in comparison with NT − proBNP ≥ 1000 pg/ml, whereas NT-proBNP reduction of >30% from initial levels did not improve 6-month outcomes and was not more effective than a traditional treatment [184–186].