However, previous acute CV events and chronic metabolic and CV diseases, such as diabetes mellitus, abdominal obesity, and hypertension, were reported to be causes of an exhausting pool of circulating angiopoetic MPCs/EPCs with immune phenotypes CD45+CD34+, CD45+CD34+CD133+, and CD45+CD34+CD133+CD184+ [221]. Here, PROM1 is linked to diabetes mellitus.