Several additional treatment-related complications have been reported recently, such as bone marrow transplantation or HSCT-induced graft-vs-host disease (GVHD), marrow infusion syndrome, and veno-occlusive disease (VOD) or sinusoidal obstruction syndrome, and immunotherapeutic agents such as interleukin-2 (IL-2) and chimeric antigen receptor T cell-induced capillary leak syndrome (CLS), which can all cause AKI associated with renal hypoperfusion. This evidence concerns the gene IL2 and acute kidney injury.