In addition, significant increase was observed in the TNF-α (Fig. 3d, g), IL-6 (Fig. 3e, h), IL-1β (Fig. 3f), and MPO (Fig. 3i) in the BALF and lung tissue samples collected from the KP-infected pneumonia mice, which were reversed by anemoside B4. Here, TNF is linked to keratosis pilaris.