KDR and neoplasm: All of these target antigens are also expressed by a range of tumor cell types, and some of them by immunosuppressive cell populations such as regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSCs, i.e., VEGFR2) (145, 146) or by the ECM (i.e., EIIIB), which may improve the outcome of the therapy in patients.