VPS13B and severe congenital neutropenia: Congenital neutropenia can also be found in association with additional immunologic and non-hematopoietic features in several syndromic disorders that are due to rare pathogenic variants in genes controlling ribosome maturation (e.g., SBDS, DNAJC21), lysosomal function (e.g., LAMTOR2, VPS13B), or glucose metabolism (e.g., G6PC3, SLC37A4), among others (13, 33) (Table 3).