Although the functional role of both FcγR common chain and FcγRIII in diet-induced atherosclerotic plaque formation in hyperlipidemic mice has been amply studied (Hernandez-Vargas et al., 2006; Kelly et al., 2010; Ng et al., 2011; Zhu et al., 2014), their specific roles in different stages of atherosclerosis have not been scrutinized. Here, FCGR2A is linked to atherosclerosis.