The temporal changes in Gal-1 expression and release underscore the involvement of Gal-1 in the resolution of inflammation, which normally resolves within 48 to 96 h in the medium dose zymosan-induced peritonitis (Bannenberg et al., 2005; Cash et al., 2009; Schif-Zuck et al., 2011). Here, GAL is linked to peritonitis.